--------1892
Domingo Escurra, an Argentinian
soldier, first reported case.
Discovered at a Buenos Aires
hospital.
--------1893
Joas Furtado-Silveira, a Portuguese
farm laborer who worked in the San
Joaquin Valley, first North American
case, dies at San Francisco
hospital.
--------1894
JosÈ Teixara Pereira, another
Portuguese farm worker, dies.
Doctors suspect a parasite and call
it Coccidioides immitis.
--------1900
Coccidioides immitis discovered to
be a fungus.
--------1905
Reports state people inhale fungal
spores to get the disease, termed
"coccidiodal granuloma."

--------1910
Immigrants to the San Joaquin
Valley develop flu-like illness known
as valley fever, or San Joaquin fever.


--------1932
The Kern County Health
Department reports non-whites
develop more serious cases.
--------1932
First published case in Mexico.
--------1932
Tests for valley fever detection are
developed.
--------1937
First Arizona case diagnosed.

--------1940s
Outbreaks among U.S. Army
soldiers in the San Joaquin Valley
and in Arizona. Outbreaks in
Japanese internment and
prisoner-of-war camps. Skin tests
performed on U.S. Airmen in the
Valley.
--------1948
First reported case in a pregnant
woman.

--------1950s
U.S. military classifies cocci as a
biological weapon. Amphotericin B
introduced as the first effective
treatment.

--------1960s
Experimental vaccines found
effective in mice and monkeys. UC
Berkeley researchers inject
themselves with the vaccine.
Vacaville Prison inmates injected
with the vaccine.

--------1970s
Outbreak among Vietnamese
refugees in California.
--------1977
Dust storm carries cocci spores all
the way to San Francisco Bay area.

--------1980s
Valley fever vaccine trials on
humans. Participants complain of
arm pain and other side effects.

--------1991
First year of Kern County epidemic
with 1,181 cases.
--------1992
Epidemic reaches peak with 3,342
cases and 25 deaths.
--------1994
Official end of 4-year epidemic.
Outbreak of valley fever in Ventura
County, following the Northridge
Earthquake. New anti-fungal drugs
available.
--------1995
Valley Fever Center for Excellence in
Tucson, Ariz., founded.

--------2000s
Cocci proteins identified that could
be used for a future vaccine.
Proteins tested on animals.
--------2001
Number of valley fever cases
rises dramatically in Arizona and
San Joaquin Valley.
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